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Agarose and acrylamide powders, buffers, diluents, markers and stains for protein/nucleic acid electrophoresis; featuring concentration, grade, melting point, capacity to stabilize, control concentration, denature, reduce, and mark target molecules.
Protein Purification Buffer, E.coli Lysis Sample buffer for HIS-TAG protein purification from E.coli and insect cells. Technical Information: pH 8.0 Na2HPO4 (50mM)NaCl (300mM)Imidazole (10mM)
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This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
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An inhibitor of H-PGDS (IC50 32 nM for the human enzyme) selective for H-PGDS over L-PGDS mPGES-1 COX-1 COX-2 and 5-LO (IC50s 10000 nM for all) inhibits PGD2 production in vivo in rat spleen at 1 mg/kg or 10 mg/kg completely inhibits allergen-induced airway hyperresponsiveness in an ovine model of asthma
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